Peter decides to go fishing with Quagmire and Joe, but when Quagmire fails to show up, they decide to try to find him at his house. After entering his home, they discover that he has hung himself in a fit of autoerotic asphyxiation. Attempting to save his life, they take him to the hospital, where they discover that he is in a coma. Peter invites Quagmire’s sister Brenda to visit him at the hospital, who manages to wake up her brother. However, Brenda also brought her abusive boyfriend, Jeff, who terrorizes her throughout the night to the dismay to Quagmire and his neighbors.

After a horrible night, Quagmire approaches Lois about talking to Brenda about leaving Jeff. At lunch, Lois and Brenda begin talking about the situation. Requesting that Brenda remove her sunglasses, she reveals a bruise over her eye, to the surprise of Lois. At the bar, Peter, Quagmire and Joe discuss the matter, asking if the police can solve the situation. Joe then suggests that the group have an intervention with Brenda, where Quagmire confesses that the sister he knew growing up no longer exists, and he wants her back. The two then embrace each other by hugging, until Jeff enters the intervention, causing Quagmire to tell him that Brenda has agreed to leave him. Frightened by Jeff, Brenda reveals that the two are engaged, and that she is pregnant.

Later that evening, Peter, Quagmire and Joe begin discussing possibly murdering Jeff, with originally Joe against it until Jeff beats Brenda for changing the channel. The three decide to talk Jeff into hunting trip in an attempt to kill him and make it look like an accident. However, having expected it, Jeff reveals his own gun and knocks Peter and Joe out so he can kill his brother-in-law in another part of the woods. Once there, Quagmire talks Jeff into fighting him instead, during which Quagmire is seemingly choked to death.

Jeff then goes to dig a grave to put Quagmire’s body in. He hears the car start up and sees Quagmire behind the wheel. When Jeff asks how he is alive, Quagmire responds “I choke myself everyday you son of a bitch” and runs Jeff over. Peter, Joe and Quagmire return home the next day, and present Brenda with a forged note from Jeff that he decided to leave her. Peter ends the episode stating that he wants to continue killing people, indicating his next victim to be Mort Goldman.

“Screams of Silence: The Story of Brenda Q” is the third episode of the tenth season of the animated comedy series Family Guy. It aired on October 30, 2011 in the United States on Fox Network.

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